Spinal Cord Tumors
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What are Brain and Spinal Tumors?Is there any treatment?What is the prognosis?What research is being done?Organizations
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What are Brain and Spinal Tumors?
Brain and spinal cord tumors are abnormal growths of tissue found inside the skull or the bony spinal column, which are the
primary components of the central nervous system (CNS). Benign tumors are noncancerous, and malignant tumors are cancerous.
The CNS is housed within rigid, bony quarters (i.e., the skull and spinal column), so any abnormal growth, whether benign
or malignant, can place pressure on sensitive tissues and impair function. Tumors that originate in the brain or spinal cord
are called primary tumors. Most primary tumors are caused by out-of-control growth among cells that surround and support neurons.
In a small number of individuals, primary tumors may result from specific genetic disease (e.g., neurofibromatosis, tuberous
sclerosis) or from exposure to radiation or cancer-causing chemicals. The cause of most primary tumors remains a mystery.
They are not contagious and, at this time, not preventable. Symptoms of brain tumors include headaches, seizures, nausea and
vomiting, vision or hearing problems, behavioral and cognitive problems, motor problems, and balance problems. Spinal cord
tumor symptoms include pain, sensory changes, and motor problems. The first test to diagnose brain and spinal column tumors
is a neurological examination. Special imaging techniques (computed tomography, and magnetic resonance imaging, positron emission
tomography) are also employed. Laboratory tests include the EEG and the spinal tap. A biopsy, a surgical procedure in which
a sample of tissue is taken from a suspected tumor, helps doctors diagnose the type of tumor.
Is there any treatment?
The three most commonly used treatments are surgery, radiation, and chemotherapy. Doctors also may prescribe steroids to reduce
the swelling inside the CNS.
What is the prognosis?
Symptoms of brain and spinal cord tumors generally develop slowly and worsen over time unless they are treated. The tumor
may be classified as benign or malignant and given a numbered score that reflects how malignant it is. This score can help
doctors determine how to treat the tumor and predict the likely outcome, or prognosis, for the patient.
What research is being done?
Researchers are studying brachytherapy (small radioactive pellets implanted directly into the tumor) and advanced drugs and
techniques for chemotherapy and radiation therapy. In gene therapy for brain and spinal cord tumors, scientists insert a gene
to make the tumor cells sensitive to certain drugs, to program the cells to self-destruct, or to instruct the cells to manufacture
substances to slow their growth. Scientists are also investigating why some genes become cancer-causing. Since tumors are
more sensitive to heat than normal tissue, research scientists are testing hyperthermia as a treatment by placing special
heat-producing antennae into the tumor region after surgery. In immunotherapy, scientists are looking for ways to duplicate
or enhance the body's immune response to fight against brain and spinal cord cancer.
Select this link
to view a list of studies currently seeking patients.
Organizations
American Brain Tumor Association (ABTA) 2720 River Road Suite 146 Des Plaines,
IL
60018-4117 info@abta.org http://www.abta.org
Tel: 847-827-9910
800-886-2282
Fax: 847-827-9918
|
Brain Tumor Society 124 Watertown Street Suite 3H Watertown,
MA
02472-2500 info@tbts.org http://www.tbts.org
Tel: 617-924-9997
800-770-TBTS (8287)
Fax: 617-924-9998
|
Childhood Brain Tumor Foundation 20312 Watkins Meadow Drive Germantown,
MD
20876 cbtf@childhoodbraintumor.org http://www.childhoodbraintumor.org
Tel: 877-217-4166
301-515-2900
|
Children's Brain Tumor Foundation 274 Madison Avenue Suite 1004 New York,
NY
10016 info@cbtf.org http://www.cbtf.org
Tel: 212-448-9494
866-CBT-HOPE (228-4673)
Fax: 212-448-1022
|
Katie's Kids for the Cure/
National Fund for Pediatric Brain Tumor Research 3741 Walnut Street Box 612 Philadelphia,
PA
19104 info@katieskids.org http://www.katieskids.org
Tel: 877-KTS-KIDS (587-5437)
610-831-9026
Fax: 215-689-1454
|
National Brain Tumor Foundation (NBTF) 22 Battery Street Suite 612 San Francisco,
CA
94111-5520 nbtf@braintumor.org http://www.braintumor.org
Tel: 415-834-9970
800-934-CURE (2873)
Fax: 415-834-9980
|
National Cancer Institute (NCI) National Institutes of Health, DHHS 6116 Executive Boulevard, Ste. 3036A, MSC 8322 Bethesda,
MD
20892-8322 cancergovstaff@mail.nih.gov http://cancer.gov
Tel: 800-4-CANCER (422-6237)
800-332-8615 (TTY)
|
Musella Foundation for Brain Tumor Research
and Information 1100 Peninsula Blvd. Hewlett,
NY
11557 musella@virtualtrials.com http://www.virtualtrials.com
Tel: 516-295-4740
888-295-4740
Fax: 516-295-2870
|
Accelerate Brain Cancer Cure, Inc. (ABC2) 1717 Rhode Island Avenue, N.W. Suite 700 Washington,
DC
20036 admin@abc2.org http://www.abc2.org
Tel: 202-419-3140
Fax: 202-419-3141
|
American Cancer Society National Home Office 1599 Clifton Road, NE Atlanta,
GA
30329-4251 http://www.cancer.org
Tel: 800-ACS-2345 (227-2345)
|
National Headache Foundation 820 N. Orleans Suite 217 Chicago,
IL
60610-3132 info@headaches.org http://www.headaches.org
Tel: 312-274-2650
888-NHF-5552 (643-5552)
Fax: 312-640-9049
|
American Council for Headache Education 19 Mantua Road Mt. Royal,
NJ
08061 achehq@talley.com http://www.achenet.org
Tel: 856-423-0258
800-255-ACHE (255-2243)
Fax: 856-423-0082
|
IRSA (International RadioSurgery Association) 3005 Hoffman Street Harrisburg,
PA
17110 office@irsa.org http://www.irsa.org
Tel: 717-260-9808
Fax: 717-260-9809
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Last updated July 20, 2007