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Thyroid  (Expert Forum)
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To Dr Mark
Questions in the Thyroid forum are answered by Dr. Mark Lupo. Topics covered include goiter, graves disease, Hashimoto's thyroiditis, hyperthyroid, hypothyroid, thyroid cancers, thyroiditis, and thyroid stimulating hormone (TSH).

To Dr Mark

by ar1281a, Aug 26, 2005 12:00AM
Based on your experience, can Thyroid disease cause Orthostatic Hypotension?
Member Comments (8)

by Mark Lupo, M.D., Aug 27, 2005 12:00AM
Yes - when thyroid levels are very high, hemodynamic (blood pressure/volume) fluctuations can result in orthostatic hypotension.  Keeping adequate fluid intake is important in this hypermetabolic state.  Also, beta-blockers such as atenolol and propanolol that are often used to treat fast heart rate and tremor of hyperthyroidism have a side-effect of orthostatic hypotension.

by ar1281a, Aug 27, 2005 12:00AM
To: drmark
Thanks so much for your reply Dr Mark!



I'm not on beta-blockers and my thyroid seems to be "within normal range" however, I'm having orthostatic hypotesion with increased heart rate, dizziness, and some ocasional tingling in my hands. Everything started with an anaphylactic reaction to what's suspected a spider bite siz weeks ago. My allergist says that at this point is not the allergy (which he confirmed with blood test) and that it might be my thyroid. My endo checked my thyroid and it seemed fine and also check for adrenal ABs which were negative. My GP has checked for the presence of viruses with all results negative. I don't mean to put you in the spot or anything, but if you have any idea it'd be greatly appreciated as right now, my Drs are out of fresh ideas. Thanks in advance! greatly appreciate your input and advice and taking the time to post on this forum.



PS I was on prednisone for 4 weeks (2 weeks ago), and currently on anti-histamines and tapazole if that helps

by ar1281a, Aug 27, 2005 12:00AM
To: drmark
oh! and I'm also having headaches

by Still_Hoping, Aug 27, 2005 12:00AM
Hi , I'm not Dr...by any means...but let me just say that antihistamines sometimes can cause some dizziness increased HR and stuff... are they sure it wasn't a tick that bit you? I know this is probably way off base...but long story short I know an RN who works with us who told us she had suddenly come up with some really odd symptoms. She had loss the feeing in her hand and stuff and was dizzy and sick and they could not figure out what it was. In the end, they treated her as if she'd had lyme disease even though to her knowledge she's not been bitten by any ticks. It took a year , she had physical therapy and drugs to treat lyme and all that ..and she recovered. But it scared her and yes she had numbness and tingles and stuff too before she lost feeling all together (not saying this will happen to you!!). So, you may look into tick bourne stuff if you have not already.  Just an idea.

by ar1281a, Aug 27, 2005 12:00AM
To: Still_Hoping
Thanks Still_Hoping,



My GP tested me for Lyme and it came back negative. I don't remember any tick bite but you never know as I spend (use to) a lot of time outside. So that's why my GP decided to r/o Lyme.



Did your RN friend tested negative for Lyme?



Thanks again



PS I hope you get better soon too

by Mark Lupo, M.D., Aug 27, 2005 12:00AM
good suggestion on the lyme disease...



did you feel significantly better on prednisone then get worse after stopping it?  Anti-histamines could do it - do they have sudafed in them (ie allegra-D, zyrtec-D etc)?



Other thoughts - acth stimulation test for adrenals (esp if symptoms got much worse after stopping pred).  Tilt table test (with a cardiologist) - most helpful if your symptoms are dizziness, nausea and sweating with prolonged standing - may not apply in your situation.  I presume your calcium, potassium and magnesium are normal.  A rare cause would be pheochromocytoma which is an overproduction of adrenalin - usually tested with 24 hour urine collection.



The spider bite history is interesting and may be important - I will think on that....

by Still_Hoping, Aug 27, 2005 12:00AM
Ar - Yes the RN that had the 'oddity' of symptoms...she was in fact negative for Lyme...but after they ruled out everything under the sun, and her hubby is an internist in town and has best friends who are in the medical community so you KNOW they took her seriously.... anyway...boy they just didn't leave any stone unturned and could not figure it out...so they decided in her case I guess..it 'looked' closer to Lyme..and so..they just treated it as such..and took a stab in the dark so to speak..and she did recover. To this day , they are not entirely sure what the problem was.  It was definitely a stumper for them all! And this lady, who is the RN is HIGHLY intelligent and does her research also but you can imagine the energy her hubby poured into this as well as all thier colleagues.  For her, this treatment worked....not sure if it will apply in your case...but... thought I'd mention it.  Boy I hate to say it but even the best docs sometimes are stumped... I'm just really glad the treatment worked for her..she said it was a long, and scary, and slowly progressive recovery - but she is fully recovered and has been fine..it's been a few years now. I don't  know the rest of her medical history she just told that story to us once in lab during a break.



Dr Mark makes some interesting suggestions as well...

by ar1281a, Aug 28, 2005 12:00AM
To: drmark-still_hoping
Thanks for your reply Dr Mark!!



I actually started to feel better when the prednisone was reduced and when I stopped it. Dizziness was better and heart rate although high was not as hig as it use to. Before it'd be 92 resting increasing to 120/130 when standing. Now, it goes from 80-85 resting to 92-95 standing. Sometimes it settles after a few minutes and sometimes it doesn't, forcing me to sit down again.



I'm not on sudafed, I'm on allegra, ranitidine, and zyrtec (I know it sounds like a lot but it was bad reaction - I guess I can talk to my allergist to reduce it). Yes, all of my electrolytes are fine (sodium, potassium, etc.) In fact, all of my blood work always comes back fine.



Thyroid has been checked three times and always comes back fine. TSH ranges b/t 0.58 and 0.76 (don't remember the T3/T4 but are ok too).



So you can see why my Drs are out of ideas.....but trying



Still_Hoping, Thanks for your message - I guess it doesn't hurt to get tested for Lyme again as ABs can be tricky to detect I hear. I know that Drs don't have all of the answers all the time, the human body is a mistery and science is still working on it! I know of cases in which people get sick and get better and they never know what happened to that person. However, I think that good Drs are those that care, don't think that what you're feeling is in your head and continue trying. Even if they can't find anything, they listen, don't think you're crazy and care. Your friend's example it's a good one in which they'll never know what happened to her. Maybe the antibiotics worked or maybe she just got better by herself, but she had a Dr who tried to help (well, personal interest but there are Drs like that out-there)



Thanks to both of you, anything you can think of is welcome. I'm ready to feel better!
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