Erin, PA has kindly answered your question in her comments below and I agree with her comprehensive assessment.
Followup with your personal physician is
essentialEssential hypertension
Essential tremor.
This answer is not intended as and does not substitute for medical advice - the information presented is for
patientKidney diet - dialysis patients education only. Please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.
Perhaps you do have low grade acid refux disease which caused your esophogitis (seen on EGD) but perhaps acid reflux disease is NOT the cause of your symtoms. This is supported by your normal 24 hour pH study, normal EMS, and most importantly, your lack of response to twice daily PPI's (multiple brands).
I would obtain a gallbladder ultrasound and perhaps a HIDA/CCK scan to look at the gallbladder which can mimick acid reflux symtoms. The 24 pH probe can be repeated with the following modifications (do it while you are on PPI's..they ususally have them hold them for 7 days). This would give an idea of if you are having inadequate acid suppression on high dose PPI's. A motility study can be repeated with provacation (they put some acid at the probe to see if it replicates your symptoms, they use water as a control, they can also put a chemical in that causes your esophagus to spasm to see if this reproduces your pain..spasm can be unrelated to acid reflux). A repeat EGD may be considered to "prove" that the esophogitis has healed, documenting acid reduction with PPI and taking esophogistis out of the mix.
Green stools are never a red flad in the GI world. Although you alteration in bowel pattern may suggest more of a bowel component to your discomfort, or even on underlying irritable bowel/functional dyspepsia cause to your symptoms. Stool studies (particularly a giardia antigen) can be obtained to rule out an infection with a paracite or bacteria and give clues to an underlying inflammations (stool for white blood cells). A colonoscopy can be done to visualize the entire colon (particularly the loops in upper right and left quadrants. This can exclude inflammation, cancer, polyps..ect. Treatment with a non-bloating fiber supplement (fiber con 2 pills/day) may be helpful. Your MD may consider other IBS medications.
Hope this helps.
Erin
GI.PA
for me it was constipation,once i switch out of it,my bowel movement returns to normal.
hope this piece of information helps.
One thing for sure, you obviously have gerd because there is esoghageal damage.
It is logical a ph and manometry would be negative if there were absolutely no symptoms at all on the day of the test. -- a repeat ph should be done -- i don't see gallbladder in the equation, it could be an additional problem to gerd of course--,and should be checked out, but certainly speculation of gallbladder disease should not be based primarily on the fact of a negative ph There were no symptoms on the day of the ph
Green stool means nothing in medicene and isn't significant . However your change of bowel habits are. You should have a stool test for bacteria etc. and colonoscopy-- particularly to view the splenic and hepatic flexures. Perhaps a gastric emptying test as well.
Yes, you have esophogeal damage and therefore GERD, but is GERD and the damage what is CAUSING the pain or just an incidental finding? If a repeat endo is done and the damage has been nicely healed but the pain remains, one would arguee that with a failure on twice daily PPI's and endoscopy proven healing, an acid related condition is very unlikely.
GI.PA
Ahhh But over have of people with gerd have negative endoscopy,ppis could have healed erosions, -- another ph test would be necessary to rule out gerd conclusively, since there were no symptoms on the first ph test. But of course an ultrasound is a good idea